where is the first and the second mixing time,

The 3D NOE-NOE intensity can be approximated by

(20.15) |

where is the energy constant specified by the SCALe statement, is the observed NOE-NOE intensities, and are error bounds, and is a scale factor specified by the RSWITch statement. The NOE-NOE connectivity and the intensity and error-bound information are provided by a pair of ASSIgn statements:

The first ASSIgn statement specifies spins and , along with the observed intensity and the error bounds and . The second ASSIgn statement specifies spins and ; the three real numbers following the second selection are irrelevant and can be set to arbitrary values. Note: the 3D NOE-NOE function can be used in combination with R-6 or center averaging. For further details, the reader is referred to Habazettl et al. (1992b,a) and Bernstein et al. (1993).