Molecular Replacement
Procedures for
molecular replacement in crystallography include
self- and cross-rotation functions, translation searches, and the
newly developed generalized molecular replacement technique
based on Patterson correlation (
) refinement
.
For further reading about -refinement, see
Brünger (1990), Brünger (1991c), and
Brünger et al. (1991).
Subsections
- Rotation Search
- Comparing Orientations of Molecules
- Translation Search
- A Mathematica Script File
- Generalized Molecular Replacement
- Self-rotation Function
- Modification of the Elbow Angle of a Known Fab Structure
- Cross-Rotation Function with the Modified Fab Structure
- PC-Refinement of the Highest Peaks of the Cross-Rotation Function
- Analysis of the PC-refinement
- Translation Function for Molecule A Using the PC-refined Model
- Translation Function for Molecule B
- Combined Translation Function to Determine the Relative Position between A and B
- Rigid-Body Refinement
- A Packing Function
- A “Direct" Rotation Function
- Generation of All Symmetry Mates
Xplor-NIH 2025-03-21